, Lavazza, Matteo1
, Pappalardo, Vincenzo1
, Inversini, Davide1
, Xiaoli, Liu2
, Wu, Che-Wei3
, Anuwong, Angkoon4
, Kim, Hoon Yub5
, Liu, Renbin6
, Gregory W. Randolph7
Division of General Surgery, Research Center for Endocrine Surgery, Department of Surgical Sciences and Human Morphology, University of Insubria (Varese-Como), via Guicciardini 9, 21100 Varese, Italy
2 Jilin Provincial Key Laboratory of Surgical Translational Medicine, Japan Union Hospital of Jilin University, Division of Thyroid Surgery, Changchun city, Jilin Province, China
3 Department of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City – Taiwan;
4 Department of Surgery, Police General Hospital, Faculty of Medicine, Siam University, Pathumwan, Bangkok, Thailand
5 KUMC Thyroid Center Korea University, Anam Hospital Seoul-Korea;
6 The Third Affilated Hospital of Sun Yat-sen University, 600 Tianhe Rd. Guangzhou 510630, China
7 Division of Thyroid and Parathyroid Surgery, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts, U.S.A.
purpose of this prospective study was to evaluate incidental thyroid cancer diagnosed by ultrasonography (US) in a population who underwent carotid echography.
Subjects & Methods: Between January 2013 and March 2016, we examined thyroid glands during routine diagnostic, follow-up carotid US. A total of 3,533 subjects underwent carotid screening ultrasound (n = 2,662) or US for diagnosis or follow-up (n = 871). When a thyroid lesion was suspicious for malignancy, fine-needle aspiration was performed. We compared the cases of pathologically proven thyroid cancer in two groups: first group, including patients with carotid disease found, and a second group, including patients with negative findings.
Results: Among the 3,533 cases, 44 (1.24%) were diagnosed as thyroid cancer; all were papillary carcinomas. Pathologically proven thyroid cancers were identified in 14 (1.6%) of the 871 patients with carotid disease and in 30 (1.12%) of the 2,662 non-vascular disease patients (p>0.05). The diameters of the 44 thyroid nodules were 0.7-3.7 cm; the mean diameters in the first and second groups were 12.9 and 11.6 mm, respectively (p>0.05).
Discussion & Conclusion:
The incidence of thyroid cancer was similar in both group. The results of routine concurrent US carotid and thyroid examinations were helpful in detecting thyroid tumors in both patient groups.