What is the difference in “Postchernobyl” and sporadic thyroid cancer features

  • Introduction.
    There are about 500 nuclear power plants in various countries and regions now. That is why hazard of nuclear disaster like Chernobyl casualty is quite presumably and we have to be ready for protecting our population, especially children (Ch), adolescents (Ad).

    Comparison of the radio-induced “Postchernobyl”” (RIPTC) in Belarus and sporadic thyroid cancer (STC) in St.Petersburg features.

    1807 ChTC and AdTC from 2 regions were studied: 1647 radioinduced ChTC from Belarus and 160 STC observations from St.Petersburg.

    A retrospective study of the Russian Ch in age from 0 to 14 has shone annually dynamics of the incidence of TC in average of 4.04%. Or 52% (6217 patients) over 10 years (2007 to 2017). Boys made 87.5%, and girls – 41.6% (per year by 0.33%).  ChTC showed extrathyroid growth in 40-50%, lymph node metastases in 40–90% and metastases in other organs – up to 20%. The risk of organ metastases increased with subcapsular or isthmus TC locations. In Belarus group during thirdpostchernobel latent period (4–9, 10–15, 16–20 years) significantly increased: the number of girls; frequency of intrathyroid TC (34.5, 40.3, 58.0%); number of MTS in 2-5 neck lymph nodes groups (34.2, 43.1, 45.7%); TC multifocality (2.8,7.6,11.0%). But, the number of MTS in the lungs decreased (14.1 to 11.0 and 2.5%.

    Patients with sporadic TC by sex, tumor sizes, regional and distant MTS, multifocality – do not differ from the “postchernobyl” TC cases of third latent period after disaster.


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