Marcia S Brose MD PhD is an Associate Professor at the University Of Pennsylvania School Of Medicine, in the Departments of Otorhinolaryngology: Head and Neck Surgery, and Medicine, Division of Hematology/Oncology. She is the Director of the Thyroid Cancer Therapeutics Program and the Director for the Center for Rare Cancers and Personalized Therapy for the Abramson Cancer Center. She received her Medical Degree from Cornell University Medical College, and her PhD in Genetics from the Rockefeller University in New York City. Dr. Brose’s primary research interest includes the identification of novel treatments for all forms of advanced thyroid cancer. She is the PI of active clinical phase I-IV clinical trials for thyroid and other rare cancers. She has been the global PI of multiple international Phase 2 and 3 studies, most recently she is the global PI of COSMIC 111 a phase 3 registration trial of cabozantinib in RAI refractory DTC.